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4C0C
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide.
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RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
MAKKTSSKGK31 LPPVYPVTVP41 FLGHIVQFGK51 NPLEFMQRCK61 RDLKSGVFTI71 SIGGQRVTIV81 GDPHEHSRFF91 SPRNEILSPR101 EVYTIMTPVF111 GEGVAYAAPY121 PRMREQLNFL131 AEELTIAKFQ141 NFVPAIQHEV151 RKFMAENWKE161 DEGVINLLED171 CGAMIINTAC181 QCLFGEDLRK191 RLNARHFAQL201 LSKMESSLIP211 AAVFMPWLLR221 LPLPQSARCR231 EARAELQKIL241 GEIIVAREKE251 EASKDNNTSD261 LLGGLLKAVY271 RDGTRMSLHE281 VCGMIVAAMF291 AGQHTSTITT301 SWSMLHLMHP311 KNKKWLDKLH321 KEIDEFPAQL331 NYDNVMDEMP341 FAERCVRESI351 RRDPPLLMVM361 RMVKAEVKVG371 SYVVPKGDII381 ACSPLLSHHD391 EEAFPNPRLW401 DPERDEKVDG411 AFIGFGAGVH421 KCIGQKFALL431 QVKTILATAF441 REYDFQLLRD451 EVPDPDYHTM461 VVGPTLNQCL471 VKYTRKKKLP SHHHHHH
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