3D View: 5FPD

Structure of heat shock-related 70kDA protein 2 with small-molecule ligand pyrazine-2-carboxamide (AT513) in an alternate binding site.

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     ​G​​S​​H​​M​​R​​G​​P​​A​​I​​G​9    ​I​​D​​L​​G​​T​​T​​Y​​S​​C​​V​19   ​G​​V​​F​​Q​​H​​G​​K​​V​​E​​I​29   ​I​​A​​N​​D​​Q​​G​​N​​R​​T​​T​39   ​P​​S​​Y​​V​​A​​F​​T​​D​​T​​E​49   ​R​​L​​I​​G​​D​​A​​A​​K​​N​​Q​59   ​V​​A​​M​​N​​P​​T​​N​​T​​I​​F​69   ​D​​A​​K​​R​​L​​I​​G​​R​​K​​F​79   ​E​​D​​A​​T​​V​​Q​​S​​D​​M​​K​89   ​H​​W​​P​​F​​R​​V​​V​​S​​E​​G​99   ​G​​K​​P​​K​​V​​Q​​V​​E​​Y​​K​109  ​G​​E​​T​​K​​T​​F​​F​​P​​E​​E​119  ​I​​S​​S​​M​​V​​L​​T​​K​​M​​K​129  ​E​​I​​A​​E​​A​​Y​​L​​G​​G​​K​139  ​V​​H​​S​​A​​V​​I​​T​​V​​P​​A​149  ​Y​​F​​N​​D​​S​​Q​​R​​Q​​A​​T​159  ​K​​D​​A​​G​​T​​I​​T​​G​​L​​N​169  ​V​​L​​R​​I​​I​​N​​E​​P​​T​​A​179  ​A​​A​​I​​A​​Y​​G​​L​​D​​K​​K​     ​G​​C​​A​​G​​G​​E​​K​​N​​V​​L​199  ​I​​F​​D​​L​​G​​G​​G​​T​​F​​D​209  ​V​​S​​I​​L​​T​​I​​E​​D​​G​​I​219  ​F​​E​​V​​K​​S​​T​​A​​G​​D​​T​229  ​H​​L​​G​​G​​E​​D​​F​​D​​N​​R​239  ​M​​V​​S​​H​​L​​A​​E​​E​​F​​K​249  ​R​​K​​H​​K​​K​​D​​I​​G​​P​​N​259  ​K​​R​​A​​V​​R​​R​​L​​R​​T​​A​269  ​C​​E​​R​​A​​K​​R​​T​​L​​S​​S​279  ​S​​T​​Q​​A​​S​​I​​E​​I​​D​​S​289  ​L​​Y​​E​​G​​V​​D​​F​​Y​​T​​S​299  ​I​​T​​R​​A​​R​​F​​E​​E​​L​​N​309  ​A​​D​​L​​F​​R​​G​​T​​L​​E​​P​319  ​V​​E​​K​​A​​L​​R​​D​​A​​K​​L​329  ​D​​K​​G​​Q​​I​​Q​​E​​I​​V​​L​339  ​V​​G​​G​​S​​T​​R​​I​​P​​K​​I​349  ​Q​​K​​L​​L​​Q​​D​​F​​F​​N​​G​359  ​K​​E​​L​​N​​K​​S​​I​​N​​P​​D​369  ​E​​A​​V​​A​​Y​​G​​A​​A​​V​​Q​379  ​A​​A​​I​​L​​I​​G​​D​
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