3D View: 5FRB

Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with a tetrazole-based inhibitor VT-1598

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Sequence of
     ​M​​A​​K​​K​​T​​P​​P​​V​​V​​F​57   ​H​​W​​F​​P​​F​​I​​G​​S​​T​​I​67   ​S​​Y​​G​​I​​D​​P​​Y​​K​​F​​F​77   ​F​​D​​C​​R​​A​​K​​Y​​G​​D​​I​87   ​F​​T​​F​​I​​L​​L​​G​​K​​K​​T​97   ​T​​V​​Y​​L​​G​​T​​K​​G​​N​​D​107  ​F​​I​​L​​N​​G​​K​​L​​R​​D​​V​117  ​C​​A​​E​​E​​V​​Y​​S​​P​​L​​T​127  ​T​​P​​V​​F​​G​​R​​H​​V​​V​​Y​137  ​D​​C​​P​​N​​A​​K​​L​​M​​E​​Q​147  ​K​​K​​F​​V​​K​​Y​​G​​L​​T​​S​157  ​D​​A​​L​​R​​S​​Y​​V​​P​​L​​I​167  ​T​​D​​E​​V​​E​​S​​F​​V​​K​​N​177  ​S​​P​​A​​F​​Q​​G​​H​​K​​G​​V​187  ​F​​D​​V​​C​​K​​T​​I​​A​​E​​I​197  ​T​​I​​Y​​T​​A​​S​​R​​S​​L​​Q​207  ​G​​K​​E​​V​​R​​S​​K​​F​​D​​S​217  ​T​​F​​A​​E​​L​​Y​​H​​N​​L​​D​227  ​M​​G​​F​​A​​P​​I​​N​​F​​M​​L​237  ​P​​W​​A​​P​​L​​P​​H​​N​​R​​K​247  ​R​​D​​A​​A​​Q​​R​​K​​L​​T​​E​257  ​T​​Y​​M​​E​​I​​I​​K​​A​​R​​R​267  ​Q​​A​​G​​S​​K​​K​​D​​S​​E​​D​277  ​M​​V​​W​​N​​L​​M​​S​​C​​V​​Y​287  ​K​​N​​G​​T​​P​​V​​P​​D​​E​​E​297  ​I​​A​​H​​M​​M​​I​​A​​L​​L​​M​307  ​A​​G​​Q​​H​​S​​S​​S​​S​​T​​A​317  ​S​​W​​I​​V​​L​​R​​L​​A​​T​​R​327  ​P​​D​​I​​M​​E​​E​​L​​Y​​Q​​E​337  ​Q​​I​​R​​V​​L​​G​​S​​D​​L​​P​347  ​P​​L​​T​​Y​​D​​N​​L​​Q​​K​​L​357  ​D​​L​​H​​A​​K​​V​​I​​K​​E​​T​367  ​L​​R​​L​​H​​A​​P​​I​​H​​S​​I​377  ​I​​R​​A​​V​​K​​N​​P​​M​​A​​V​387  ​D​​G​​T​​S​​Y​​V​​I​​P​​T​​S​397  ​H​​N​​V​​L​​S​​S​​P​​G​​V​​T​407  ​A​​R​​S​​E​​E​​H​​F​​P​​N​​P​417  ​L​​E​​W​​N​​P​​H​​R​​W​​D​​E​427  ​N​​I​​A​​A​​S​​A​​E​​D​​D​​E​437  ​K​​V​​D​​Y​​G​​Y​​G​​L​​V​​S​447  ​K​​G​​T​​N​​S​​P​​Y​​L​​P​​F​457  ​G​​A​​G​​R​​H​​R​​C​​I​​G​​E​467  ​Q​​F​​A​​Y​​L​​Q​​L​​G​​T​​I​477  ​T​​A​​V​​L​​V​​R​​L​​F​​R​​F​487  ​R​​N​​L​​P​​G​​V​​D​​G​​I​​P​497  ​D​​T​​D​​Y​​S​​S​​L​​F​​S​​K​507  ​P​​L​​G​​R​​S​​F​​V​​E​​F​​E​517  ​K​​R​​H​
Type
Asm Id
Dynamic Bonds

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