3D View: 5MUT

Crystal structure of potent human Dihydroorotate Dehydrogenase inhibitors based on hydroxylated azole scaffolds

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
32   ​T​​G​​D​​E​​R​​F​​Y​​A​​E​​H​42   ​L​​M​​P​​T​​L​​Q​​G​​L​​L​​D​52   ​P​​E​​S​​A​​H​​R​​L​​A​​V​​R​62   ​F​​T​​S​​L​​G​​L​​L​​P​​R​​A​     ​R​​F​​Q​​D​​S​​D​​M​​L​​E​​V​82   ​R​​V​​L​​G​​H​​K​​F​​R​​N​​P​92   ​V​​G​​I​​A​​A​​G​​F​​D​​K​​H​102  ​G​​E​​A​​V​​D​​G​​L​​Y​​K​​M​112  ​G​​F​​G​​F​​V​​E​​I​​G​​S​​V​122  ​T​​P​​K​​P​​Q​​E​​G​​N​​P​​R​132  ​P​​R​​V​​F​​R​​L​​P​​E​​D​​Q​142  ​A​​V​​I​​N​​R​​Y​​G​​F​​N​​S​152  ​H​​G​​L​​S​​V​​V​​E​​H​​R​​L​162  ​R​​A​​R​​Q​​Q​​K​​Q​​A​​K​​L​172  ​T​​E​​D​​G​​L​​P​​L​​G​​V​​N​182  ​L​​G​​K​​N​​K​​T​​S​​V​​D​​A​192  ​A​​E​​D​​Y​​A​​E​​G​​V​​R​​V​202  ​L​​G​​P​​L​​A​​D​​Y​​L​​V​​V​212  ​N​​V​​S​​S​​P​​N​​T​​A​​G​​L​     ​R​​S​​L​​Q​​G​​K​​A​​E​​L​​R​232  ​R​​L​​L​​T​​K​​V​​L​​Q​​E​​R​242  ​D​​G​​L​​R​​R​​V​​H​​R​​P​​A​252  ​V​​L​​V​​K​​I​​A​​P​​D​​L​​T​262  ​S​​Q​​D​​K​​E​​D​​I​​A​​S​​V​272  ​V​​K​​E​​L​​G​​I​​D​​G​​L​​I​282  ​V​​T​​N​​T​​T​​V​​S​​R​​P​​A​292  ​G​​L​​Q​​G​​A​​L​​R​​S​​E​​T​302  ​G​​G​​L​​S​​G​​K​​P​​L​​R​​D​312  ​L​​S​​T​​Q​​T​​I​​R​​E​​M​​Y​322  ​A​​L​​T​​Q​​G​​R​​V​​P​​I​​I​332  ​G​​V​​G​​G​​V​​S​​S​​G​​Q​​D​342  ​A​​L​​E​​K​​I​​R​​A​​G​​A​​S​352  ​L​​V​​Q​​L​​Y​​T​​A​​L​​T​​F​362  ​W​​G​​P​​P​​V​​V​​G​​K​​V​​K​372  ​R​​E​​L​​E​​A​​L​​L​​K​​E​​Q​382  ​G​​F​​G​​G​​V​​T​​D​​A​​I​​G​392  ​A​​D​​H​​R​​R​
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