V308E mutant of cytochrome P450 2D6 complexed with thioridazine

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RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
     ​M​​A​​K​​K​​T​​S​​S​​K​​G​​K​33   ​L​​P​​P​​G​​P​​L​​P​​L​​P​​G​     ​L​​G​​N​​L​​L​​H​​V​​D​​F​​Q​53   ​N​​T​​P​​Y​​C​​F​​D​​Q​​L​​R​63   ​R​​R​​F​​G​​D​​V​​F​​S​​L​​Q​73   ​L​​A​​W​​T​​P​​V​​V​​V​​L​​N​83   ​G​​L​​A​​A​​V​​R​​E​​A​​L​​V​93   ​T​​H​​G​​E​​D​​T​​A​​D​​R​​P​103  ​P​​V​​P​​I​​T​​Q​​I​​L​​G​​F​113  ​G​​P​​R​​S​​Q​​G​​V​​F​​L​​A​123  ​R​​Y​​G​​P​​A​​W​​R​​E​​Q​​R​133  ​R​​F​​S​​V​​S​​T​​L​​R​​N​​L​143  ​G​​L​​G​​K​​K​​S​​L​​E​​Q​​W​153  ​V​​T​​E​​E​​A​​A​​C​​L​​C​​A​163  ​A​​F​​A​​N​​H​​S​​G​​R​​P​​F​173  ​R​​P​​N​​G​​L​​L​​D​​K​​A​​V​183  ​S​​N​​V​​I​​A​​S​​L​​T​​C​​G​193  ​R​​R​​F​​E​​Y​​D​​D​​P​​R​​F​203  ​L​​R​​L​​L​​D​​L​​A​​Q​​E​​G​213  ​L​​K​​E​​E​​S​​G​​F​​L​​R​​E​223  ​V​​L​​N​​A​​V​​P​​V​​L​​L​​H​233  ​I​​P​​A​​L​​A​​G​​K​​V​​L​​R​243  ​F​​Q​​K​​A​​F​​L​​T​​Q​​L​​D​253  ​E​​L​​L​​T​​E​​H​​R​​M​​T​​W​263  ​D​​P​​A​​Q​​P​​P​​R​​D​​L​​T​273  ​E​​A​​F​​L​​A​​E​​M​​E​​K​​A​283  ​K​​G​​N​​P​​E​​S​​S​​F​​N​​D​293  ​E​​N​​L​​R​​I​​V​​V​​A​​D​​L​303  ​F​​S​​A​​G​​M​​E​​T​​T​​S​​T​313  ​T​​L​​A​​W​​G​​L​​L​​L​​M​​I​323  ​L​​H​​P​​D​​V​​Q​​R​​R​​V​​Q​333  ​Q​​E​​I​​D​​D​​V​​I​​G​​Q​​V​343  ​R​​R​​P​​E​​M​​G​​D​​Q​​A​​H​353  ​M​​P​​Y​​T​​T​​A​​V​​I​​H​​E​363  ​V​​Q​​R​​F​​G​​D​​I​​V​​P​​L​373  ​G​​V​​T​​H​​M​​T​​S​​R​​D​​I​383  ​E​​V​​Q​​G​​F​​R​​I​​P​​K​​G​393  ​T​​T​​L​​I​​T​​N​​L​​S​​S​​V​403  ​L​​K​​D​​E​​A​​V​​W​​E​​K​​P​413  ​F​​R​​F​​H​​P​​E​​H​​F​​L​​D​423  ​A​​Q​​G​​H​​F​​V​​K​​P​​E​​A​433  ​F​​L​​P​​F​​S​​A​​G​​R​​R​​A​443  ​C​​L​​G​​E​​P​​L​​A​​R​​M​​E​453  ​L​​F​​L​​F​​F​​T​​S​​L​​L​​Q​463  ​H​​F​​S​​F​​S​​V​​P​​T​​G​​Q​473  ​P​​R​​P​​S​​H​​H​​G​​V​​F​​A​483  ​F​​L​​V​​S​​P​​S​​P​​Y​​E​​L​493  ​C​​A​​V​​P​​R​​H​​H​​H​​H​
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