3TOG
HIV-1 Protease - Epoxydic Inhibitor Complex (pH 9 - Monoclinic Crystal form P21)
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d3togb_ | All beta proteins | Acid proteases | Acid proteases | Retroviral protease (retropepsin) | Human immunodeficiency virus type 1 protease | HIV-1 (Human immunodeficiency virus type 1 (BRU ISOLATE) ) [TaxId: 11686 ], | SCOPe (2.08) |
C | d3togc_ | All beta proteins | Acid proteases | Acid proteases | Retroviral protease (retropepsin) | Human immunodeficiency virus type 1 protease | HIV-1 (Human immunodeficiency virus type 1 (BRU ISOLATE) ) [TaxId: 11686 ], | SCOPe (2.08) |
D | d3togd_ | All beta proteins | Acid proteases | Acid proteases | Retroviral protease (retropepsin) | Human immunodeficiency virus type 1 protease | HIV-1 (Human immunodeficiency virus type 1 (BRU ISOLATE) ) [TaxId: 11686 ], | SCOPe (2.08) |
A | d3toga_ | All beta proteins | Acid proteases | Acid proteases | Retroviral protease (retropepsin) | Human immunodeficiency virus type 1 protease | HIV-1 (Human immunodeficiency virus type 1 (BRU ISOLATE) ) [TaxId: 11686 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Acid proteases | 8036828 | 3001059 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Acid proteases | 8036828 | 3001059 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Acid proteases | 8036828 | 3001059 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Acid proteases | 8036828 | 3001059 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | RVP | e3togB1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: RVP | ECOD (1.6) |
C | RVP | e3togC1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: RVP | ECOD (1.6) |
D | RVP | e3togD1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: RVP | ECOD (1.6) |
A | RVP | e3togA1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: RVP | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
C | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
D | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
A | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00077 | Retroviral aspartyl protease (RVP) | Retroviral aspartyl protease | Single domain aspartyl proteases from retroviruses, retrotransposons, and badnaviruses (plant dsDNA viruses). These proteases are generally part of a larger polyprotein; usually pol, more rarely gag. Retroviral proteases appear to be homologous to a ... | Domain |