4BRB

Crystal structure of the integral membrane enzyme DgkA-ref, delta 7

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4brba_	Membrane and cell surface proteins and peptides	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
B	d4brbb_	Membrane and cell surface proteins and peptides	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
D	d4brbd_	Membrane and cell surface proteins and peptides	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
E	d4brbe_	Membrane and cell surface proteins and peptides	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
C	d4brbc_	Membrane and cell surface proteins and peptides	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
F	d4brbf_	Membrane and cell surface proteins and peptides	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)-like	Diacylglycerol kinase (DgkA)	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	DAGK_prokar	e4brbA1	A: alpha bundles	X: Diacylglycerol kinase (DAGK) (From Topology)	H: Diacylglycerol kinase (DAGK) (From Topology)	T: Diacylglycerol kinase (DAGK)	F: DAGK_prokar	ECOD (1.6)
B	DAGK_prokar	e4brbB1	A: alpha bundles	X: Diacylglycerol kinase (DAGK) (From Topology)	H: Diacylglycerol kinase (DAGK) (From Topology)	T: Diacylglycerol kinase (DAGK)	F: DAGK_prokar	ECOD (1.6)
D	DAGK_prokar	e4brbD1	A: alpha bundles	X: Diacylglycerol kinase (DAGK) (From Topology)	H: Diacylglycerol kinase (DAGK) (From Topology)	T: Diacylglycerol kinase (DAGK)	F: DAGK_prokar	ECOD (1.6)
E	DAGK_prokar	e4brbE1	A: alpha bundles	X: Diacylglycerol kinase (DAGK) (From Topology)	H: Diacylglycerol kinase (DAGK) (From Topology)	T: Diacylglycerol kinase (DAGK)	F: DAGK_prokar	ECOD (1.6)
C	DAGK_prokar	e4brbC1	A: alpha bundles	X: Diacylglycerol kinase (DAGK) (From Topology)	H: Diacylglycerol kinase (DAGK) (From Topology)	T: Diacylglycerol kinase (DAGK)	F: DAGK_prokar	ECOD (1.6)
F	DAGK_prokar	e4brbF1	A: alpha bundles	X: Diacylglycerol kinase (DAGK) (From Topology)	H: Diacylglycerol kinase (DAGK) (From Topology)	T: Diacylglycerol kinase (DAGK)	F: DAGK_prokar	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.287.3610	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
B	1.10.287.3610	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
D	1.10.287.3610	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
E	1.10.287.3610	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
C	1.10.287.3610	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
F	1.10.287.3610	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF01219	Prokaryotic diacylglycerol kinase (DAGK_prokar)	Prokaryotic diacylglycerol kinase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	DIACYLGLYCEROL KINASE	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding kinase activity lipid kinase activity transferase activity ATP-dependent diacylglycerol kinase activity catalytic activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups cation binding metal ion binding identical protein binding protein binding	phosphatidic acid biosynthetic process glycerophospholipid biosynthetic process phosphatidic acid metabolic process glycerophospholipid metabolic process lipid biosynthetic process primary metabolic process phospholipid biosynthetic process phospholipid metabolic process biosynthetic process glycerolipid biosynthetic process organophosphate metabolic process organophosphate biosynthetic process phosphate-containing compound metabolic process glycerolipid metabolic process phosphatidic acid biosynthetic process glycerophospholipid biosynthetic process phosphatidic acid metabolic process glycerophospholipid metabolic process lipid biosynthetic process primary metabolic process phospholipid biosynthetic process phospholipid metabolic process biosynthetic process glycerolipid biosynthetic process organophosphate metabolic process organophosphate biosynthetic process phosphate-containing compound metabolic process glycerolipid metabolic process metabolic process cellular process phosphorus metabolic process lipid metabolic process response to light stimulus response to stimulus response to radiation response to abiotic stimulus response to UV	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR000829	DAGK family	Family
A, B, C, D, E A, B, C, D, E, F	IPR033718	Diacylglycerol kinase, prokaryotic	Family
A, B, C, D, E A, B, C, D, E, F	IPR036945	Diacylglycerol kinase (DAGK) superfamily	Homologous Superfamily

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F	MemProtMD	Annotated as membrane protein by MemProtMD

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.