Annotations: 7ASL

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
E [auth I]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
F [auth N]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
H [auth J]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
I [auth O]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
J [auth F]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
L [auth P]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
M [auth G]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
N [auth L]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
O [auth Q]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
P [auth H]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
Q [auth M]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)
G [auth E]	SCOP2B Superfamily	Retrovirus capsid dimerization domain-like	8077052	3001819	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Gag_p24_C	e7aslA2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
A	Gag_p24_N	e7aslA1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
B	Gag_p24_C	e7aslB2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
B	Gag_p24_N	e7aslB1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
C	Gag_p24_C	e7aslC1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
C	Gag_p24_N	e7aslC2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
D	Gag_p24_C	e7aslD1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
D	Gag_p24_N	e7aslD2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
E [auth I]	Gag_p24_C	e7aslI2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
E [auth I]	Gag_p24_N	e7aslI1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
F [auth N]	Gag_p24_C	e7aslN1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
F [auth N]	Gag_p24_N	e7aslN2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
H [auth J]	Gag_p24_C	e7aslJ2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
H [auth J]	Gag_p24_N	e7aslJ1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
I [auth O]	Gag_p24_C	e7aslO1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
I [auth O]	Gag_p24_N	e7aslO2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
J [auth F]	Gag_p24_C	e7aslF2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
J [auth F]	Gag_p24_N	e7aslF1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
K	Gag_p24_C	e7aslK2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
K	Gag_p24_N	e7aslK1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
L [auth P]	Gag_p24_C	e7aslP2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
L [auth P]	Gag_p24_N	e7aslP1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
M [auth G]	Gag_p24_C	e7aslG2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
M [auth G]	Gag_p24_N	e7aslG1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
N [auth L]	Gag_p24_C	e7aslL1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
N [auth L]	Gag_p24_N	e7aslL2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
O [auth Q]	Gag_p24_C	e7aslQ1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
O [auth Q]	Gag_p24_N	e7aslQ2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
P [auth H]	Gag_p24_C	e7aslH2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
P [auth H]	Gag_p24_N	e7aslH1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
Q [auth M]	Gag_p24_C	e7aslM2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
Q [auth M]	Gag_p24_N	e7aslM1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
R	Gag_p24_C	e7aslR1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
R	Gag_p24_N	e7aslR2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)
G [auth E]	Gag_p24_C	e7aslE1	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein-C (From Topology)	T: Retrovirus capsid protein-C	F: Gag_p24_C	ECOD (1.6)
G [auth E]	Gag_p24_N	e7aslE2	A: alpha bundles	X: Retrovirus capsid protein	H: Retrovirus capsid protein N-terminal domain (From Topology)	T: Retrovirus capsid protein N-terminal domain	F: Gag_p24_N	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	PF00607	gag protein p24 N-terminal domain (Gag_p24)	gag protein p24 N-terminal domain	p24 forms inner protein layer of the nucleocapsid. ELISA tests for p24 is the most commonly used method to demonstrate virus replication both in vivo and in vitro.	Domain
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	PF19317	Gag protein p24 C-terminal domain (Gag_p24_C)	Gag protein p24 C-terminal domain	p24 forms inner protein layer of the nucleocapsid. ELISA tests for p24 is the most commonly used method to demonstrate virus replication both in vivo and in vitro.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	Gag protein	structural molecule activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding organic cyclic compound binding nucleic acid binding	viral gene expression viral process viral translational frameshifting viral translation virion assembly viral budding viral budding via host ESCRT complex viral life cycle	host intracellular membrane-bounded organelle host cellular component host intracellular part host multivesicular body host cell cytoplasm part host intracellular organelle cellular anatomical structure host cell cytoplasm host cell part host cell late endosome host cell endosome host intracellular region membrane virion component host intracellular membrane-bounded organelle host cellular component host intracellular part host multivesicular body host cell cytoplasm part host intracellular organelle cellular anatomical structure host cell cytoplasm host cell part host cell late endosome host cell endosome host intracellular region membrane virion component virion membrane host cell nuclear membrane host cell membrane host cell nucleus host cell nuclear part host cell endomembrane system host cell nuclear envelope host cell plasma membrane viral nucleocapsid viral capsid

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR000071	Immunodeficiency lentiviral matrix, N-terminal	Domain
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR045345	Retroviral nucleocapsid Gag protein p24, C-terminal domain	Domain
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR036875	Zinc finger, CCHC-type superfamily	Homologous Superfamily
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR050195	Primate lentivirus group Gag polyprotein-like	Domain
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR001878	Zinc finger, CCHC-type	Domain
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR008919	Retrovirus capsid, N-terminal	Homologous Superfamily
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR010999	Retroviral matrix protein	Homologous Superfamily
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR012344	Matrix protein, lentiviral and alpha-retroviral, N-terminal	Homologous Superfamily
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR014817	Gag protein p6	Domain
A, B, C, D, E [auth I], A, B, C, D, E [auth I], F [auth N], G [auth E], H [auth J], I [auth O], J [auth F], K, L [auth P], M [auth G], N [auth L], O [auth Q], P [auth H], Q [auth M], R	IPR008916	Retrovirus capsid, C-terminal	Homologous Superfamily