Chemical Component Summary

NameASCORBIC ACID
SynonymsVitamin C
Identifiers(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-5H-furan-2-one
FormulaC6 H8 O6
Molecular Weight176.124
TypeL-SACCHARIDE
Isomeric SMILESC([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O
InChIInChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChIKeyCIWBSHSKHKDKBQ-JLAZNSOCSA-N

Chemical Details

Formal Charge0
Atom Count20
Chiral Atom Count2
Bond Count20
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB00126 
NameAscorbic acid
Groups
  • approved
  • nutraceutical
DescriptionA six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Synonyms
  • Vitamina C
  • acide ascorbique
  • acidum ascorbinicum
  • Acidum ascorbicum
  • L-Ascorbic Acid
Brand Names
  • Calcium Magnesium Avec Vitamine C
  • ProFola
  • Selenium 200mcg Plus C & E Tab
  • Hemarexin Tab
  • PR Natal 400 ec
IndicationUsed to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
Categories
  • Acids, Acyclic
  • Alimentary Tract and Metabolism
  • Antioxidants
  • Biological Factors
  • Carbohydrates
ATC-Code
  • G01AD03
  • A11GA01
  • A11GB01
  • S01XA15
CAS number50-81-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Hyaluronate lyaseMQTKTKKLIVSLSSLVLSGFLLNHYMTIGAEETTTNTIQQSQKEVQYQQR...unknowninhibitor
DNA-unknowncleavage
Xylose isomeraseMNYQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVRRLAELGAHG...unknownsubstrate
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESD...unknowncofactor
Phytanoyl-CoA dioxygenase, peroxisomalMEQLRAAARLQIVLGHLGRPSAGAVVAHPTSGTISSASFHPQQFQYTLDN...unknowncofactor
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL196
PubChem 54670067
ChEMBL CHEMBL196, CHEMBL40274
ChEBI CHEBI:29073
CCDC/CSD LASCAC14, LASCAC15, RUWFEV, OXOGUF, SERASC10, IASCOR10, LASCAC12, COFKOA, ERAVAU, COFKOA01, OXOHAM, COFKOA02, OXOHEQ, OXOHIU, KABCAV01, KABCAV, OXOHEQ01
COD 2108681, 4501794, 2108680, 2300646, 2300647, 2300648