CK2

4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE

Created:	2003-07-07
Last modified:	2021-03-13

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3 entries where CK2 is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	24
Chiral Atom Count	0
Bond Count	25
Aromatic Bond Count	12

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Chemical Component Summary
Name	4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-AMINE
Synonyms	4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINE
Systematic Name (OpenEye OEToolkits)	4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine
Formula	C₉ H₁₀ N₄ S
Molecular Weight	206.267
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n2c(c1sc(nc1C)C)ccnc2N
SMILES	CACTVS	3.341	Cc1sc(c(C)n1)c2ccnc(N)n2
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc(n1)C)c2ccnc(n2)N
Canonical SMILES	CACTVS	3.341	Cc1sc(c(C)n1)c2ccnc(N)n2
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc(n1)C)c2ccnc(n2)N
InChI	InChI	1.03	InChI=1S/C9H10N4S/c1-5-8(14-6(2)12-5)7-3-4-11-9(10)13-7/h3-4H,1-2H3,(H2,10,11,13)
InChIKey	InChI	1.03	CTFDMGIBHFQWKB-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB02091
Name	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
Groups	experimental
Synonyms	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cyclin-A2	MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAAL...	unknown
Cyclin-dependent kinase 2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682