FUM
FUMARIC ACID
Find entries where: FUM
is present as a standalone ligand in 60 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries
is present in a polymer sequence 3 entries
Chemical Component Summary | |
|---|---|
| Name | FUMARIC ACID |
| Identifiers | (E)-but-2-enedioic acid |
| Formula | C4 H4 O4 |
| Molecular Weight | 116.072 |
| Type | NON-POLYMER |
| Isomeric SMILES | C(=C/C(=O)O)\C(=O)O |
| InChI | InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+ |
| InChIKey | VZCYOOQTPOCHFL-OWOJBTEDSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 12 |
| Chiral Atom Count | 0 |
| Bond Count | 11 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB01677 |
|---|---|
| Name | Fumaric acid |
| Groups | investigational |
| Synonyms |
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| Categories |
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| ATC-Code | D05AX01 |
| CAS number | 110-17-8 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Malate dehydrogenase | MRKKISIIGAGFVGSTTAHWLAAKELGDIVLLDFVEGVPQGKALDLYEAS... | unknown | |
| Fumarate reductase flavoprotein subunit | MFTRKIQKTALAMLISGAMAGTAYAAPEVLADFHGEMGGCDSCHVSDKGG... | unknown | |
| NAD-dependent malic enzyme, mitochondrial | MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGL... | unknown | |
| Fumarylacetoacetase | MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLF... | unknown | |
| Fumarate reductase flavoprotein subunit | ADNLAEFHVQNQECDSCHTPDGELSNDSLTYENTQCVSCHGTLEEVAETT... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 21883788, 444972 |
| ChEMBL | CHEMBL503160 |
| ChEBI | CHEBI:18012, CHEBI:22958 |
| CCDC/CSD | FICTAO, COCPEQ, DOQCOE, DUTNUC, ACERUX, AJALEC, ECANOO, FEMKIR, AJAHIC, ENICIO, BASZAY, COGCUZ, AXUFUV, BATDUX, FOTFIF, DIKDIL, CUXTEX, FIBHOP, DIFNUC, DOGCOU, EDAPOQ, ERIKUL, FIBBUQ, FOTCUO, BICQEL, FUMAAC, EYOYUM, AXUGAC, FOTDEZ, BOYGOO, DODFUX10, EVATED, EZAQII, AWITIM, ETUBUT, ETUCAA |
| COD | 7214487, 7217952, 7214478, 7217943, 7214477, 7217942, 7214488, 7217953, 2101617, 7214489, 7217954, 7214479, 7217944, 7208188 |
