HYP

4-HYDROXYPROLINE

Find entries where: HYP

is present as a standalone ligand in 10 entries

is present in a polymer sequence 367 entries

Find related ligands:

Similar Ligands (Stereospecific)

Similar Ligands (Quick Screen)

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	4-HYDROXYPROLINE
Synonyms	HYDROXYPROLINE
Identifiers	(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
Formula	C₅ H₉ N O₃
Molecular Weight	131.13
Type	L-PEPTIDE LINKING
Isomeric SMILES	C1[C@H](CN[C@@H]1C(=O)O)O
InChI	InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
InChIKey	PMMYEEVYMWASQN-DMTCNVIQSA-N

Chemical Details
Formal Charge	0
Atom Count	18
Chiral Atom Count	2
Bond Count	18
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB08847
Name	Hydroxyproline
Groups	experimental
Description	Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved in France as a combination topical gel product called Cicactive for small, superficial wounds.
Synonyms	Hydroxyproline trans-L-Hydroxyproline trans-4-Hydroxy-L-proline
Brand Names	Cathycat Chewy CREAM FOUNDATION SPF23 PA WHITENING ANTI WRINKLE 21 Soo Rye Han Dabityun Jiyun Foundation 21 Isaknox Timeless Essence Foundation 21 Sooryehan Onbit Essence Foundation 23 Ohui Skin Science Age Recovery Cell Lab Eye Ohui Skin Science Age Recovery Cell Lab The History Of Whoo Gongjinhyang Mi Pact 2 Isa Knox Ageless Serum Makeup Base 10 Gongjinhyang Mi Luxury Foundation 1 Ohui Skin Science Age Recovery Cell-lab Essential The History Of Whoo Gongjinhyang Mi Pact 1 Isa Knox Tervina Repair Foundation Bb O Hui Wrinkle Science Deep Wrinkle Treatment Sooryehan Onbit Essence Foundation 25 O Hui Wrinkle Science Wrinkle Repair Sooryehan Onbit Lifting Base Isa Knox Wrinkle Decline Double Effect Rf3 Wrinkle Eye Filler Gongjinhyang Mi Luxury Foundation 2 Cathycat Chewy CREAM FOUNDATION SPF23 PA WHITENING ANTI WRINKLE 23 Isa Knox Smart Bb Sun Ohui The First Cell Revolution Age Control Sun Block Isaknox Timeless Essence Foundation 23 OHUI Wrinkle Science wrinkle repair eye Soo Rye Han Dabityoon Jiyoon Foundation 23 Isaknox Ageless Serum Moist Pearl Base Ouhi Cell Power No 1 Essence Ouhi Cell Power No 1 Eye Isa Knox Wrinkle Decline Double Effect Rf3 Wrinkle The History of Whoo Bichup Ja Saeng Essence Isaknox Timeless Essence Makeup Base 70 Ohui Skin Science Age Recovery Cell Lab Essence Ageless Foundation 23 Ohui Skin Science Age Recovery Cell Lab Pramin Gongjinhyang Mi Luxury Base
Indication	Used in France as a combination product for the treatment of small, superficial wounds.
Categories	Amino Acids Amino Acids, Cyclic Amino Acids, Peptides, and Proteins Imino Acids
CAS number	51-35-4

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Proton-coupled amino acid transporter 1	MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWF...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682