Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
Synonyms
1-hydroxy-2-methoxybenzene
Pyroguaiac acid
o-hydroxyanisole
Guaiacol carbonate
o-Methoxyphenol
2-methoxyl-4-vinylphenol
Pyrocatechol monomethyl ether
Guaiacol
Guaiacol hydrochloride
2-methoxyphenol
o-guaiacol
Brand Names
Pastilles Valda
Valda Pastilles
Demo Cineol Inj
Demo-cineol Adultes/adults
Jamp-cough Suppositories Adult
Jamp-suppositories Children
Analgesic Balm
Creo-rectal Nourrisson
Demo-cineol Enfants/children
Dentalgar Liq
Dry Socket
Creo-rectal Enfants/children
Valda Pastilles Lemon Flavoured
Creo-rectal Adultes/adults
Gouttes Dentaires
Indication
It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
