SCF

5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine

Created:	2007-09-20
Last modified:	2011-06-04

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1 entries where SCF is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	38
Chiral Atom Count	0
Bond Count	41
Aromatic Bond Count	23

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Chemical Component Summary
Name	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
Systematic Name (OpenEye OEToolkits)	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[5,1-b]pyrimidin-7-amine
Formula	C₁₈ H₁₄ F N₅
Molecular Weight	319.336
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	Fc4ccccc4c2nc1ccnn1c(c2)NCc3ccncc3
SMILES	CACTVS	3.341	Fc1ccccc1c2cc(NCc3ccncc3)n4nccc4n2
SMILES	OpenEye OEToolkits	1.5.0	c1ccc(c(c1)c2cc(n3c(n2)ccn3)NCc4ccncc4)F
Canonical SMILES	CACTVS	3.341	Fc1ccccc1c2cc(NCc3ccncc3)n4nccc4n2
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1ccc(c(c1)c2cc(n3c(n2)ccn3)NCc4ccncc4)F
InChI	InChI	1.03	InChI=1S/C18H14FN5/c19-15-4-2-1-3-14(15)16-11-18(24-17(23-16)7-10-22-24)21-12-13-5-8-20-9-6-13/h1-11,21H,12H2
InChIKey	InChI	1.03	ZAIYYXVHGBMLEC-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB08534
Name	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
Groups	experimental
Synonyms	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cyclin-dependent kinase 2	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682