6BG6
Crystal structure of S111A mutant of human macrophage migration inhibitory factor
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d6bg6b_ | Alpha and beta proteins (a+b) | Tautomerase/MIF | Tautomerase/MIF | MIF-related | Microphage migration inhibition factor (MIF) | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
A | d6bg6a_ | Alpha and beta proteins (a+b) | Tautomerase/MIF | Tautomerase/MIF | MIF-related | Microphage migration inhibition factor (MIF) | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
C | d6bg6c_ | Alpha and beta proteins (a+b) | Tautomerase/MIF | Tautomerase/MIF | MIF-related | Microphage migration inhibition factor (MIF) | Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | MIF | e6bg6B1 | A: a+b two layers | X: Tautomerase/MIF-like | H: Tautomerase/MIF (From Topology) | T: Tautomerase/MIF | F: MIF | ECOD (1.6) |
A | MIF | e6bg6A1 | A: a+b two layers | X: Tautomerase/MIF-like | H: Tautomerase/MIF (From Topology) | T: Tautomerase/MIF | F: MIF | ECOD (1.6) |
C | MIF | e6bg6C1 | A: a+b two layers | X: Tautomerase/MIF-like | H: Tautomerase/MIF (From Topology) | T: Tautomerase/MIF | F: MIF | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.30.429.10 | Alpha Beta | 2-Layer Sandwich | Macrophage Migration Inhibitory Factor | Macrophage Migration Inhibitory Factor | CATH (4.3.0) |
A | 3.30.429.10 | Alpha Beta | 2-Layer Sandwich | Macrophage Migration Inhibitory Factor | Macrophage Migration Inhibitory Factor | CATH (4.3.0) |
C | 3.30.429.10 | Alpha Beta | 2-Layer Sandwich | Macrophage Migration Inhibitory Factor | Macrophage Migration Inhibitory Factor | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01187 | Macrophage migration inhibitory factor (MIF) (MIF) | Macrophage migration inhibitory factor (MIF) | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001398 | Macrophage migration inhibitory factor | Family | |
IPR019829 | Macrophage migration inhibitory factor, conserved site | Conserved Site | |
IPR014347 | Tautomerase/MIF superfamily | Homologous Superfamily |