Annotations: 5FSE


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad5fsea_ Alpha and beta proteins (a+b) Urease, gamma-subunit Urease, gamma-subunit Urease, gamma-subunit automated matches (Sporosarcina pasteurii ) [TaxId: 1474 ], SCOPe (2.08)
Bd5fseb_ All beta proteins beta-clip Urease, beta-subunit Urease, beta-subunit Urease, beta-subunit (Sporosarcina pasteurii ) [TaxId: 1474 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyUrease, gamma-subunit 8034247 3001945 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyUrease, beta-subunit 8043131 3001949 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMetallo-dependent hydrolases 8043430 3000428 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyComposite domain of metallo-dependent hydrolases 8043172 3000176 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AUrease_gammae5fseA1 A: a+b two layersX: Urease, gamma-subunit (From Topology)H: Urease, gamma-subunit (From Topology)T: Urease, gamma-subunitF: Urease_gammaECOD (1.6)
BUrease_betae5fseB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Urease, beta-subunit (From Topology)T: Urease, beta-subunitF: Urease_betaECOD (1.6)
CUrease_alphae5fseC2 A: beta sandwichesX: Composite domain of metallo-dependent hydrolases (From Topology)H: Composite domain of metallo-dependent hydrolases (From Topology)T: Composite domain of metallo-dependent hydrolasesF: Urease_alphaECOD (1.6)
CAmidohydro_1_Ne5fseC1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Amidohydro_1_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.280.10 Alpha Beta 2-Layer Sandwich Urease subunit ACATH (4.3.0)
B2.10.150.10 Mainly Beta Ribbon Urease, subunit B Urease, beta subunitCATH (4.3.0)
C2.30.40.10 Mainly Beta Roll Urease, subunit C domain 1CATH (4.3.0)
C3.20.20.140 Alpha Beta Alpha-Beta Barrel TIM Barrel Metal-dependent hydrolasesCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00547Urease, gamma subunit (Urease_gamma)Urease, gamma subunitUrease is a nickel-binding enzyme that catalyses the hydrolysis of urea to carbon dioxide and ammonia.Domain
PF00699Urease beta subunit (Urease_beta)Urease beta subunitThis subunit is known as alpha in Heliobacter.Domain
PF00449Urease alpha-subunit, N-terminal domain (Urease_alpha)Urease alpha-subunit, N-terminal domainThe N-terminal domain is a composite domain and plays a major trimer stabilising role by contacting the catalytic domain of the symmetry related alpha-subunit.Domain
PF01979Amidohydrolase family (Amidohydro_1)Amidohydrolase familyThis family of enzymes are a a large metal dependent hydrolase superfamily [1]. The family includes Adenine deaminase EC:3.5.4.2 that hydrolyses adenine to form hypoxanthine and ammonia. Adenine deaminases reaction is important for adenine utilisatio ...Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
UREASE SUBUNIT GAMMA
UREASE SUBUNIT BETA
UREASE SUBUNIT ALPHA

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
CXM Parent Component: MET

RESIDAA0363 , AA0493

PSI-MOD :  N-carboxy-L-methionine MOD:00368 , N-(dihydroxymethyl)-L-methionine (fMet) MOD:01446 , N-(dihydroxymethyl)-L-methionine (Met) MOD:01447
KCX Parent Component: LYS

RESIDAA0363 , AA0493